follow

Leading the Fight to treat and cure
Tay-Sachs, Canavan, Sandhoff, GM1 and related diseases

  • 1
  • 2
  • 3
  • 4
  • 1
  • 2
  • 3

All of our genes code for specific proteins, which have specific roles in our bodies. The PLP1 gene provides the code to build proteolipid protein 1, and a similar protein called DM20. These are the main proteins which are found in myelin. If the PLP1 gene contains a mutation, these proteins will not be made. If these proteins are not made then the myelin sheath cannot be formed correctly. This leads to the symptoms of Pelizaeus-Merzbacher disease.

Sign up for news

 

Enter your email to receive NTSAD's Topic of the Week or quarterly news.


 

Enter your email to receive NTSAD's Topic of the Week or quarterly news.


Login