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Leading the Fight to treat and cure
Tay-Sachs, Canavan and related diseases

Apply for a Grant

NTSAD's Research Initiative funds research that may lead to treatments for lysosomal storage diseases or leukodystrophies impacting the central nervous system (CNS).  NTSAD solicits proposals annually for innovative research projects that involve basic research, translational studies or clinical studies.  Basic research and translational studies should generate strong preliminary data to enable future major funding.

All proposals are reviewed and evaluated by members of the NTSAD Scientific Advisory Committee and other qualified scientists. The final decision of award recipients is determined by the Research Initiative Committee of the NTSAD Board of Directors.

Funding for the grants comes from gifts made to NTSAD's Research Initiative from NTSAD's chapters and affiliates as well as donations and fundraising events.  

 Download the 2014-2015 Request for Proposals Application and Guidelines here.

Grants will be awarded for an initial period of one year at $40,000 direct costs per year (10% indirect cost rate); funding for a second year is predicated by adequate progress during year 1.The application will use a two-step process. First, a one page pre-application will be submitted.From these pre-applications, investigators will be chosen to submit a full application. The application format and review criteria are specified on page 2 of this RFP. The deadline for submission of pre-applications is January 9, 2015.

NTSAD is soliciting proposals for innovative research projects that involve basic research, translational studies or clinical studies in the areas of neurodegenerative disorders affecting the CNS, especially lysosomal storage disorders (such as Tay-Sachs, GM-1, Sandhoff) and pediatric leukodystrophies (such as Canavan). Basic research and translational studies should generate strong preliminary data to enable future major funding by other third parties. Projects may be in such areas as drug delivery to the brain, new animal models designed to facilitate translational research and drug discovery, assay development for drug screening, substrate reduction, stem cells, molecular chaperones, gene therapy, and biomarkers, as well as exploring other novel therapeutic strategies.

 

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